miércoles, 3 de diciembre de 2014

Skeleton in car park is Richard III beyond all reasonable doubt

A comprehensive DNA and genealogical study confirms the identity of the remains found underneath a Leicester car park and uncovers new truths about the appearance of Richard III and the Plantagenet lineage.
An international research team led by Dr Turi King from the University of Leicester Department of Genetics published their results in Nature Communications.

Genetic markers

The researchers collected DNA from living relatives of Richard III and analysed several genetic markers, including the complete mitochondrial genomes, inherited through the maternal line, and Y-chromosomal markers, inherited through the paternal line, from both the skeletal remains and the living relatives.
While the Y-chromosomal markers differ, the mitochondrial genome shows a genetic match between the skeleton and the maternal line relatives. The former result is not unsurprising as the chances for a false-paternity event is fairly high after so many generations. This paper is also the first to carry out a statistical analysis of all the evidence together to prove beyond reasonable doubt that Skeleton 1 from the Greyfriars site in Leicester is indeed the remains of King Richard III.
The researchers also used genetic markers to determine hair and eye colour of Richard III and found that he probably had blond hair and almost certainly had blue eyes. This means that he looked most similar to his depiction in one of the earliest portraits of him that has survived; now hanging at the Society of Antiquaries in London.

Plans to sequence the complete genome of King

The research team now plans to sequence the complete genome of Richard III to learn more about the last English king to die in battle.
Dr King said, “Our paper covers all the genetic and genealogical analysis involved in the identification of the remains of Skeleton 1 from the Greyfriars site in Leicester and is the first to draw together all the strands of evidence to come to a conclusion about the identity of those remains. Even with our highly conservative analysis, the evidence is overwhelming that these are indeed the remains of King Richard III, thereby closing an over 500 year old missing person’s case.”
Professor Schürer added, “The combination of evidence confirms the remains as those of Richard III. Especially important is the triangulation of the maternal line descendants. The break in the Y-chromosome line is not overly surprising given the incidence of non-paternity, but does pose interesting speculative questions over succession as a result.

Source: Past Horizons: http://www.pasthorizonspr.com/index.php/archives/12/2014/skeleton-in-car-park-is-richard-iii-beyond-all-reasonable-doubt

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